Abrupt cessation of therapy with a beta-blocker should be avoided especially in patients with ischaemic heart disease. When possible, metoprolol should be withdrawn gradually over a period of 10 days, the doses diminishing to 25mg for the last 6 days. Metoprolol tartrate tablets should be administered orally. The tablets should be taken on an empty stomach. The dose must always be adjusted to the individual requirements of the patient. Important Information. You should not use Metoprolol Tartrate Tartrate if you have a serious heart problem (heart block, sick sinus syndrome, slow heart rate), severe circulation problems, severe heart failure, or a history of slow heart beats that caused fainting. Lopressor® (metoprolol tartrate) Injection, USP (metoprolol tartrate) InjectionDESCRIPTION. Lopressor, metoprolol tartrate USP, is a selective beta1-adrenoreceptor blocking agent, available in 5- mL ampuls for intravenous administration. Metoprolol is a beta-blocker that affects the heart and circulation (blood flow through arteries and veins). Metoprolol is used to treat angina (chest pain) and hypertension (high blood pressure). It is also used to lower your risk of death or needing to be hospitalized for heart failure. Metoprolol How to use Metoprolol Tartrate. See also Warning section. Take this medication by mouth, with or right after a meal, as directed by your doctor, usually 1-3 times a day. Metoprolol Tartrate reference guide for safe and effective use from the American Society of Health-System Pharmacists (AHFS DI). If you have a heart attack, your doctor may give you metoprolol tartrate (Lopressor). This drug can prevent another heart attack from occurring. (Detail-Document 250302: Page 3 of 3) 3. Poole-Wilson PA, Swedberg K, Cleland JG, et al. Comparison of carvedilol and metoprolol on clinical Lopressor (metoprolol tartrate) Tablets and Injection is a selective beta-adrenoreceptor blocking agent (beta-blocker) used to treat high blood presure (hypertension), angina, and heart attacks.